Atorvastatin Calcium
PRODUCT IDENTIFICATION
CAS NO. 134523-03-8
EINECS NO. FORMULA (C33H34FN2O5)2Ca3H2O MOL WT. 1209.42
H.S. CODE
TOXICITY
SYNONYMS Lipitor; (-)-Monocalcium bis[(3R, 5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-phenylcarbamoyl-1H- pyrrol-1-yl]-3,5-dihydroxyheptanoate] Trihydrate; [R-(R',R')]-2-(4-fluorophenyl)-beta,delta- dihydroxy-5-( 1-methylethyl)-3-phenyl-4 [(phenylamino) carbonyl]- lH-pyrrole-1-heptanoic acid, calcium salt (2:1) Trihydrate; Atorvastatinis a member of the drug class known as statins, used for lowering blood cholesterol.
It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms.Atorvastatin inhibits HMG-CoA reductase, the rate-determining enzyme located in hepatic tissue that produces mevalonate, a small molecule used in the synthesis of cholesterol and other mevalonate derivatives.
This lowers the amount of cholesterol produced which in turn lowers the total amount of LDL cholesterol.
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE: white to off-white crystalline powder
- AUTOIGNITION
- NFPA RATINGS
- REFRACTIVE INDEX
- FLASH POINT
- STABILITY
Stable under ordinary conditions. SALES SPECIFICATION
- APPEARANCE: white to off-white crystalline powder
- IDENTIFICATION: Complies (Test A,B)
- ASSAY: 98.0% - 101.0%
- CALCIUM: 3.3% - 3.6%
- WATER: 7.0% max
- LOSS ON DRYING: 0.5% max
- Usage: Antihyperlipidemia
TRANSPORTATION
PACKING :
1kg/tin or as per your requirement
Characteristics: A white or almost white crystalline powder
- Specific rotation: -7.0 ~ -9.0
- Water: 3.5% ~ 5.5%
- Calcium: 3.0% ~ 3.6%
- Heavy metals: 10ppm
Impurity (HPLC):
- Atorvastatin Lactone: 0.3%
- Desfluoro-atorvastatin calcium: 0.2%
- Diamine-atorvastatin calcium: 0.3%
- Isomer-atorvastatin calcium: 0.2%
- Other individual:
HAZARD CLASS: UN NO.
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 22-24/25
Origin: INDIA
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