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Anthranilic Acid
CAS number 118-92-3
Anthranilic acid is the organic compound with the formula C6H4(NH2)CO2H. This amino acid is white solid when pure, although commercial samples may appear yellow. The molecule consists of a benzene ring with two adjacent functional groups, a carboxylic acid and an amine. Because these two groups are polar, this organic compound is highly soluble in water. It is sometimes referred to as vitamin.
Hazards
MSDS External (html)
R-phrases R36 R37
S-phrases S26 S39
Flash point >150 °C
Synonyms:
o-Aminobenzoic acid; 2-Carboxyaniline; Anthranilic acid; Benzoic acid, o-amino-; Kyselina o-aminobenzoova [Czech]; Anthranilate; o-Carboxyaniline; ortho-Aminobenzoic acid; 2-Aminobenzoic acid; ANTHRANILIC ACID; Benzoic acid, 2-amino-; Kyselina anthranilova [Czech]; 1-Amino-2-carboxybenzene; 2-Aminobenzoate; Caswell No. 033G; Vitamin L1; BRN 0471803; o-Anthranilic acid; NCI-C01730; AI3-02408
Uses
Anthranilic acid is used as an intermediate for production of dyes, pigments, and saccharin. It and its esters are used in preparing perfumes to imitate jasmine and orange, pharmaceuticals (loop diuretics eg. furosemide) and UV-absorber as well as corrosion inhibitors for metals and mold inhibitors in soya sauce. PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE White to pale yellow crystalline powder
MELTING POINT : 146 - 148 C
BOILING POINT Sublimes
SPECIFIC GRAVITY 1.412
SOLUBILITY IN WATER Freely soluble
AUTOIGNITION
pH
VAPOR DENSITY 4.7
NFPA RATINGS Health: 1 Flammability: 1 Reactivity: 0 APPLICATIONS
Anthranilic acid is the organic compound with the formula C6H4(NH2)COOH. This amino acid is white solid when pure, although commercial samples may appear yellow. The molecule consists of a benzene ring with two adjacent functional groups, a carboxylic acid and an amine. It is sometimes referred to as vitamin L.
Biological role
Anthranilic acid is biosynthesized from chorismic acid. It is the precursor to the amino acid tryptophan via the attachment of phosphoribosyl pyrophosphate to the amine group. *** SHELF LIFE UNLIMITED IN UNOPENED CONTAINERS
SOLUBILITY
ACETONE AND ESTERS
READILY SOLUBLE INETHANOL
SUGGESTED APPLICATION
INTERMEDIATE FOR THE CHEMICAL
INDUSTRY,
eg. FOR THE MANUFACTURE OF
DYES,PHARMACEUTICALS AND
PERFUMERY SYNTHETICS
SALES SPECIFICATION
APPEARANCE: White to pale yellow crystalline powder
PURITY (G.C) :99.0% min
ASH: 0.2% max
MOISTURE: 0.5% max
MELTING POINT
146 ± 1.5 C
TRANSPORTATION
PACKING 25kgs in Bag
Anthranilic acid can be used in organic synthesis to generate the benzyne intermediate.
| TYPES OF HAZARD / EXPOSURE |
ACUTE HAZARDS / SYMPTOMS |
PREVENTION |
FIRST AID / FIRE FIGHTING |
| FIRE |
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
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NO open flames.
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Powder, water spray, foam, carbon dioxide.
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| EXPLOSION |
Finely dispersed particles form explosive mixtures in air.
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Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.
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| EXPOSURE |
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| Inhalation |
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Local exhaust or breathing protection.
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Fresh air, rest. |
| Skin |
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Protective gloves.
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Rinse and then wash skin with water and soap.
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| Eyes |
Redness. Pain.
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Safety spectacles
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First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
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| Ingestion |
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Do not eat, drink, or smoke during work.
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Rinse mouth. Give one or two glasses of water to drink. Seek medical attention if you feel unwell
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