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Testosterone
- CAS number 58-22-0
- 57-85-2 (propionate ester)s
- ATC code G03BA03
- Pub Chem 6013
- Chem Spider 5791
Product name Testosterone
CAS number 58-22-0
Chemical Name (17b)-17-Hydroxyandrost-4-en-3-one
Biological Activity Endogenous androgen receptor agonist.
Physical Appearance: White crystalline solid
Technical Data:
M.Wt: 288.42
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity: >98 %
Storage: Store at RT
Analytical Data Optical Rotation: []D = +109.9 (Concentration = 1, Solvent = Ethanol)
Chemical data
Formula C19H28O2
Mol. mass 288.42
SMILES eMolecules & PubChem
Physical data
Melt. point 155™156 °C (311 313 °F)
Spec. rot +110,2°
SEC Combust 11080 kJ/mol
Pharmacokinetic data
Bioavailability low (due to extensive first pass metabolism)
Metabolism Liver, Testis and Prostate
Half life 2-4 hours
Excretion Urine (90%), feces (6%)
Hazards Identification
RTECS substance category: Tumorigen; Drug; Mutagen; Reproductive Effector; Hormone Exposure may cause irritation to eyes, mucous membranes, upper respiratory tract and skin. Exposure may also cause the following: spermatogenesis, specific developmental abnormalities, physical effects on newborns, abortion, effects on fertility, tumorigenic effects,
endocrine changes. Effect fertility and/or newborn and breastfed infants.
Toxicological Information
To the best of our knowledge, the chemical, physical and toxicological properties have not been fully investigated.
RTECS No: XA3030000
Target Organs: Eyes; Respiratory system; Skin; Reproductive system;
Endocrine system.
Toxicity Data: IPR-RAT LDLo: 326mg/kg; ORL-MAM LD50: >5gm/kg.
Limited evidence has been reported to suggest this
product is carcinogenic
Only selected Registry of Toxic Effects of Chemical Substances (RTECS) data is presented above. See actual entry in RTECS for complete information.
Regulatory Information
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin
Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instruction before use
Risk Phrases: R40 - Limited evidence of a carcinogenic effect
R60 - May impair fertility
R61 - May cause harm to the unborn child
R68 - Possible risk of irreversible effects
Other Information
Due to the nature of this material. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The above information is believed to be correct but does not purport to be all inclusive and should be used as a guide only for experienced personnel. Always consult your safety advisor and follow appropriate local and national safety legislature. The absence of warning must not, under any circumstance, be taken to mean that no hazard exists.
Solubility & Useage Info:
DMSO to 100 mM
ethanol to 25 mM
Stability and Solubility Advice:
Some solutions can be difficult to obtain and can be encouraged by rapid stirring, sonication or gentle warming (in a 45-60 °C water bath).
Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. Our standard recommendations are:
SOLIDS: Provided storage is as stated on the product label and the vial is kept tightly sealed, the product can be stored
for up to 6 months from date of receipt.
SOLUTIONS: We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°
C or below and used within 1 month. Wherever possible solutions should be made up and used on the same day.
Other Derivatives of Testosterone
1. TESTOSTERONE PHENYLPROPIONATE
2. TESTOSTERONE DECANOATE
3. TESTOSTERONE UNDECANOATE
4. TESTOSTERONE ENANTHATE
5. TESTOSTERONE ISOCAPROATE
6. TESTOSTERONE PROPIONATE
1. Testosterone Phenylpropionate
Chemical name: 4-Androsten-17-ol-3-one Phenpropionate
Name: TESTOSTERONE PHENYLPROPIONATE
Appearance: white or almost white crystalline powder
Molecular Formula: C28H36O3
Molecular Weight: 420.583640 [g/mol]
EINECS: 215-01 4-4
InChIKey: HHSXYDOROIURIP-FEZCWRLCSA-N
Density: 1.13g/cm3
Boiling Point: 546.90Cat760mmHg
Flash Point: 233.30C
EINECS: 215-014-4
Specification: BP2003
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IUPAC Name: [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate
- CAS Registry Number: 1255-49-8
- Synonyms: Retandrol, Testolent, Testosterone phenylpropionate, Testosterone phenpropionate, Testosterone, hydrocinnamate, Testosterone 17-phenylpropionate, Testosterone hydrocinnamate, T9890_SIGMA, EINECS 215-014-4, NSC 26643, BB_NC-0581, NSC26643, TESTOSTERONE PHENYL PROPIONATE, ZINC03881605, 17beta-Hydroxyandrost-4-en-3-one 3-phenylpropionate, LS-148821, C14667, 4-Androsten-17beta-ol-3-one 17-phenylpropionate, 1255-49-8, Androst-4-en-3-one, 17-(1-oxo-3-phenylpropoxy)-, (17-beta)-
Background
Testosterone was first synthesized by being isolated from bulls testicles in 1935. Many pharmaceutical forms and derivatives have been created since.
This version of Testosterone was originally manufactured by the Sicomed Pharmaceutical house under the brand name, ½ For many years, Testosterone Phenylpropionate was difficult to obtain but has recently been made more available by underground labs.
Chemical data
Formula C9H10O2
Testosterone phenylpropionate is a slow-acting ester, with a release time of 1-3 weeks. A popular name brand for T-phenylpropionate is "Testolent." Testosterone phenylpropionate is also one of the components of Sustanon and Omnadren.
Testosterone is a hormone produced predominantly in the testes of males. It is responsible for nearly all of the sexual traits in males. This specific version is Testosterone with the Phenylpropionate ester attached. It has an active life of 4-5 day. Release time-wise, it is directly in the middle of the Propionate (short) and Cypionate (long) versions of Testosterone. It is recommended to inject this version two times per week, although many prefer every third day.
Technical Data Testosterone's anabolic/androgenic effects are dependant upon the dose administered; usually the higher the dose, the better the results. In a study done on Testosterone (Enanthate), a dose as high as 600 mg's (per week) produced better results in subjects compared to those who received lower doses. At the highest dose, 600 mg/week, the greatest results were achieved in comparison to any of the lower doses studied. The highest fat loss, most muscle growth, and increased size and strength were achieved at the higher dose. In the same study, HDL cholesterol was lowered and the subjects experienced acne. There was roughly a 15% gain in Lean Body Mass from 20 weeks of 600 mg/week of Testosterone therapy.
Overall, the most common report by subjects using testosterone was immense gains in strength as well as alterations in size, shape, and appearance of the muscle.
Due to stimulation of the Androgen Receptors (either directly or as DHT), accelerated muscle gain, fat loss, increased muscle repair and growth was experienced. Testosterone binds to the A.R. on fat cells; therefore, adipose (fat) tissue can be broken down more readily while new fat formation is prevented. Since the body is building muscle at an accelerated rate, more ingested food is shuttled directly to the muscle tissue (this is known as nutrient portioning) and away from fat. This is another indirect effect of testosterone on fat loss. Testosterone also promotes glycogen synthesis, which is activated by insulin in response to high glucose levels. Glycogen provides fuel to the muscle; therefore endurance and strength increases were reported during severe muscle breakdown in intense training and workouts.
2. Testosterone Decanoate
Cas No 5721-91-5
CBNumber: CB9748594
Chemical Name: Testosterone decanoate
Drug Class: Injectable Anabolic Steroid
Synonyms:TESTOSTERONE 17-N-DECANOATE;testosterone caproate;TESTOSTERONE DECANOATE;testosteronedecanoate--dea*scheduleiiiitem;17-BETA-HYDROXY-4-ANDROSTEN-3-ONE-DECANOATE;17b-hydroxyandrost-4-en-3-one decanoate;4-ANDROSTEN-17BETA-OL-3-ONE 17-N-DECANOATE;4-ANDROSTEN-17-BETA-OL-3-ONE DECANOATE;Testosterone Decaonate;17beta-hydroxyandrost-4-en-3-one decanoate;Testosateronedecanoate;Androst-4-en-3-one, 17-(1-oxodecyl)oxy-, (17.beta.)-;[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] decanoate;17-Hydroxy-androst-4-en-3-one-17-decanoate;17-Hydroxy-4-androsten-3-one 17-decanoate, 4-Androsten-17Ãol-3-one 17-caprate;17(1-Oxodecyloxy)androst-4-en-3-one
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Molecular Formula:
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C29H46O3
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Molecular Weight:
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442.67
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| Hazard Codes : |
Xn |
Risk Statements :
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20/21/22-40 |
Safety Statements :
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22-36 |
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| Testosterone decanoate Chemical Properties,Usage,Production |
| Testosterone decanoate Preparation Products And Raw materials |
| Raw materials |
| Preparation Products |
EINECS: 227-226-4
Density: 1.04 g/cm3
Boiling Point: 539.2 ° C at 760 mmHg
Flash Point: 226.4 ° C
Appearance: White to almost white crystalline
3. Testosterone Undecanoate
Systematic (IUPAC) name(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo- 1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]undecanoate CAS #: 5949-44-0
Purity: 98.0%
Physical and Chemical Properties
Physical state: Solid
Color: White
Freezing/Melting Point: 64-65 deg C
Solubility: Insoluble in water
Chemical Stability: Stable under normal temperatures and pressures.
Materials to avoid: Strong oxidizing agents.
Conditions to Avoid: Incompatible materials.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Has not been reported.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Regulatory Information European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Xi Indication of Danger: Irritant Risk Phrases: R 22 Harmful if swallowed. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. WGK ( Water Danger/Protection)
Chemical data
- Formula: C30H48O3
- Mol. mass: 456.70032
- SMILES: eMolecules & PubChem
Pharmacokinetic data
- Bioavailability: 7%
- Metabolism: Liver, Testis and Prostate
- Half-life: 1-12 days
- Excretion: Urine
Therapeutic considerations
- Pregnancy cat.: X (USA), Teratogenic effects
- Legal status: Schedule III (USA), Schedule IV (Canada)
- Routes: Oral, I.V
Testosterone undecanoate also known as testosterone undecylate, Andriol, Undestor, Nebido, Pantestone, Restandol, and Nebido-R is an ester of testosterone which is used for the treatment of male hypogonadism.It is also available in an injectable form (Reandron 1000).[1]
Andriol, is a version of the anabolic steroid Testosterone Undecanoate developed by the pharmaceutical company Organon. This testosterone preparation is encapsulated and sealed in an oil base in a 40 mg capsule taken orally. According to Organon, this method bypasses the liver, preventing it from being damaged by the liver and from adding damaging stresses to the liver found in other testosterone preparations. It is said to enter the body as a fat through the lymphatic system. Experience from users indicates that in doses of less than 240mg per day, effects are negligible, except at the very onset of use, while even in higher doses, effects are still minimal. It is therefore thought that most of the steroid is somehow not making it into the blood stream.
4.Testosterone Enanthate
17-Hydroxy-4-androsten-3-one17-enanthate 4-Androsten-17-3-one 17-enanthate, Testosterone 17-heptanoate
TESTOSTERONE ENANTHATE--DEA*SCHEDULE III
testosterone enthanoate
17-hydroxy-4-androsten-3-one 17-enanthate
17b-hydroxyandrost-4-en-3-one-17-ethanate
17BETA-HYDROXY-4-ANDROSTEN-3-ONE 17-ENANTHATE
4-ANDROSTEN-17-BETA-OL-3-ONE ENANTHATE
Chemical IUPAC Name
[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate
Chemical Taxonomy
Kingdom
Organic
Super Class
Cholesterols and derivatives
Class
Steroids and Steroid Derivatives
Sub Class
Ketosteroids
Family
Mammalian Metabolite
Species
ketone
carboxylic acid ester
alkene
Biofunction
Hormones, Membrane component
Application
½
Source
Exogenous
Average Molecular Weight 400.594
Monoisotopic Molecular Weight 400.297760
Isomeric SMILES CCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=
CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Canonical SMILES CCCCCCC(=O)OC1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C
InChI Identifier nChI=1/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20- 10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3 /h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/m0/s1
Synthesis Reference Ulrich, Miroslav; Novacek, Alois; Stejskal, Frantisek. Testosterone enanthate. (1960), CS 95825 19600615 CAN 55:81895 AN 1961:81895
Melting Point
(Experimental) 36-37.5 oC
Predicted Water Solubility 4.63e-04 mg/mL [Predicted by ALOGPS]; 5.43e-06 mg/mL
at 25 oC [MEYLAN,WM et al. (1996)]
Physiological Charge 0
State Solid
Predicted LogP/Hydrophobicity 5.11 [Predicted by ALOGPS]; 5.6 [Predicted by PubChem via XLOGP]; 6.73 [MEYLAN,WM &
HOWARD,PH (1995)]
Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Flash Points CLOSED CUP: Higher than 93.3°C (200°F).
Products of Combustion These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances Non-flammable in presence of shocks.
Testosterone Enanthate
Special Remarks on Sensitive to light.
Reactivity
Polymerization Will not occur.
Toxicological Information
Routes of Entry Absorbed through skin. Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): >1000 mg/kg [Rat].
Chronic Effects on Humans
TERATOGENIC EFFECTS: Classified POSSIBLE for human.
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
[POSSIBLE].
May cause damage to the following organs: blood, the reproductive system, liver.
Other Toxic Effects on Humans
Slightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.
Special Remarks on Chronic Effects on Humans
May affect genetic material (mutagenic).
May cause adverse reproductive effects and birth defects (teratogenic).
May cause cancer
Ecological Information
Products of Biodegradation
Possibly hazardous short term degradation products are not likely. However, long term degradation products mayarise.
Toxicity of the Products of Biodegradation
The products of degradation are less toxic than the product itself.
Waste Disposal
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Other Regulations
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Description:
Testosterone enanthate
is used in androgen substitution to replace testosterone at levels as close to physiological levels as is possible. For some androgen-dependent functions testosterone is a pro-hormone, peripherally converted to 5alpha-dihydrotestosterone (DHT) and 17beta-estradiol (E2), of which the levels preferably should be within normal physiological ranges. Furthermore, androgens should have a good safety profile without adverse effects on the prostate, serum lipids, liver or respiratory function, and they must be convenient to use and patient-friendly, with a relative independence from medical services. Natural testosterone is viewed as the best androgen for substitution in hypogonadal men. testosterone enanthate is used to treat male hypogonadism. Male hypogonadism is one of the most common endocrinologic syndromes. The diagnosis is based on clinical signs and symptoms plus laboratory confirmation via the measurement of low morning testosterone levels on two different occasions. Serum luteinizing hormone and follicle-stimulating hormone levels distinguish between primary (hypergonadotropic) and secondary (hypogonadotropic) hypogonadism. Osteoporosis in male hypogonadism: responses to androgen substitution differ among men with primary and secondary hypogonadism. In primary hypogonadal men the on bone mineral density (BMD) responds dose dependently to testosterone substitution, whereas in secondary hypogonadism only testosterone enanthate treatment significantly increased the BMD. In all mammalian species studied to date, testosterone has been found to be the predominant intratesticular steroid. In volunteers receiving hormonal contraception by using a combination of testosterone enanthate and levonorgestrel, there is a profound reduction of both intratesticular testosterone concentration and androgen bioactivity. High doses of testosterone enanthate can normalize hematocrit values of maintenance hemodialysis patients with replenished bone marrow iron stores. testosterone enanthate is classified as a prohibited substance by the World Anti-Doping Agency (WADA) and its use may be detected by way of the urinary testosterone/epitestosterone (T/E) ratio. (PMID: 16185098, 16467270, 15329035, 17530941, 17484401, 4028529, 12792150)
5. Testosterone Isocaproate
Synonyms:
17beta-hydroxyandrost-4-ene-3-one 4-methylvalerate;4-ANDROSTEN-17-BETA-OL-3-ONE ISOCAPROATE;4-ANDROSTEN-17BETA-OL-3-ONE ISOCAPRONATE;4-ANDROSTEN-17BETA-OL-3-ONE 17[4-METHYLPENTANOATE];4-androsten-17b-ol-3-one 17-[4-methylpentanoate];TESTOSTERONE ISOCAPROATE;TESTOSTERONE ISOCAPRONATE;TESTOSTERONE 4-METHYLVALERATE;testosterone isocaproate--dea*schedule iii item;Androst-4-en-3-one, 17-(4-methyl-1-oxopentyl)oxy-, (17.beta.)-;4-androsten-17-3-one 17-(4-methylpentanoate);Testosterone 17-isohexanoate;TESTOSTERONE4-METHYLPENTANOATE;4-Androsten-17-3-one 17-(4-methylpentanoate), Testosterone 4-methylvalerate;17-(4-Methylvaleryloxy)androsta-4-ene 3-one;17-[(4-Methyl-1-oxopentyl)oxy]androst-4-en-3-one
IUPAC Name: (10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl) 4-methylpentanoate Synonyms of Testosterone isocaproate (CAS NO.15262-86-9): EINECS 239-307-1 ; NSC 26641 ; 17beta-Hydroxyandrost-4-ene-3-one 4-methylvalerate ; Androst-4-en-3-one, 17-((4-methyl-1-oxopentyl)oxy)-, (17beta)- Classification Code: Hormone ; Reproductive Effect
Polar Surface Area: 43.37 2
Index of Refraction: 1.529
Molar Refractivity: 111.19 cm3
Molar Volume: 360.3 cm3
Surface Tension: 40.7 dyne/cm
Density of Testosterone isocaproate : 1.07 g/cm3
Flash Point: 208 °C
Enthalpy of Vaporization: 75.35 kJ/mol
Boiling Point: 487.6 °C at 760 mmHg
Vapour Pressure: 1.17E-09 mmHg at 25°C
Properties: white or almost white crystalline powder
Einecs : 239-307-1
Assay: 97.0%
Appearance white fine powder
Molecular Formula C25H38O3
Molecular Weight 386.5674
CAS Registry Number 15262-86-9
EINECS 239-307-1
Optional Information - HS Code : 3006 Pharmaceutical Goods Description: This product is white crystalline powder.It can be used to cause weight and strength gain, fat loss, a libido increase, an increase in IGF-1 levels, red blood cell count, and of course increased recovery from training. It will also convert to estrogen and dihydrotestosterone, causing possible water retention and gynocomastia as well as acne and hairloss, respectively. Safety Profile:
Hazard Codes of Testosterone isocaproate (CAS NO.15262-86-9): Harmful Xn
Risk Statements: 20/21/22-40
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 22-36
S22: Do not breathe dust.
S36: Wear suitable protective clothing.
WGK Germany: 3
(Testosterone Isocaproate)
Testosterone Isocaproate got its introduction to the steroid world by appearing in both Omnadren as well as Sustanon 250, the two most popular testosterone blends currently on the market.
From a purely academic point of view, I'm really at a loss to explain why the isocaproate ester would be any different than the caproate ester. It seems to have an extra day added to its active life, even though it's got the same number of carbons, hydrogens, and oxygens, as well as the same molecular weight.
As I just mentioned, this is a form of esterfied testosterone, or in other words, it's the testosterone hormone bound to a fatty acid (the ester) to delay its release into the body. The isocaproate ester has a decently long active life in the body, and consequently there's no reason to inject this more than once every week.
As with all forms of testosterone, this product will cause weight and strength gain, fat loss, a libido increase, an increase in IGF-1 levels, Red Blood Cell count, and of course increased recovery from training. It will also convert to Estrogen and Dihydrotestosterone, causing possible water retention and gynocomastia as well as acne and hairloss, respectively.
As with all forms of injectable testosterone , using this product will shut down your body's own natural production of testosterone. Also, in many cases, cholesterol, immune function, and several other health markers may be adversely affected by the use of this product.
4-androstene-3-one, 17beta-ol
(Testosterone Base + Isocaproate Ester)
Molecular Weight(base): 288.429
Molecular Weight (ester): 116.1596
Formula (base): C19 H28 O2
Formula (ester): C6 H12 O2
Melting Point (base): 155 C
Melting Point (ester): -35
Manufacturer: 31-32 C
Effective Dose (Men): 250-1,000mgs/week
Active life: 8 days
Detection Time: Up to 6 weeks
Anabolic: Androgenic ratio: 100:1006. Testosterone Propionate Pharmaceutical Name: Testosterone (as Propionate)
Chemical structure: 4-androstene-3-one,17beta-ol
Molecular weight of base: 288.429
Molecular weight of ester: 74.0792 (propionic acid, 3 carbons)
CAS Number: 57-85-2
EINECS NO. 200-351-1 FORMULA C22H32O3
MOL WT. 344.49
Specification USP28/BP2003
Synonyms Testosteroni propionas;
17-(1-oxopropoxy)-(17beta)-androst-4-en-3-one; 3-Oxo-4-androsten-17beta-yl propionate; delta4-androstene-17b-propionate-3-one; testosterone-17beta-propionate; 17beta-Propionyloxy-4-androsten-3-one; 17beta-Hydroxy-4-androsten-3-one 17-propionate; 4-Androsten-17beta-ol-3-one 17-propionate;
DERIVATION
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 118 - 121 C
NFPA RATINGS Health: 2 Flammability: 0 Reactivity: 0
STABILITY Stable under ordinary conditions
APPLICATIONS
Testosterone is the major androgenic hormone that is responsible for the growth and development of masculine characteristics. It is produced in the Leydig cells (interstitial cells) of the testes. it regulates gonadotropic secretion and wolffian duct differentiation (formation of the epididymis, vas deferens, and seminal vesicle), and stimulates skeletal muscle. It is also responsible for other male characteristics and spermatogenesis after its conversion to dihydrotestosterone by 5alpha-reductase in peripheral tissue. Testosterone is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone.
SALES SPECIFICATION
APPEARANCE White to off-white crystalline powder
ASSAY 97.0 - 103.0%
MELTING POINT 118 - 121 C
WATER SOLUBILITY Insoluble
OPTICAL ROTATION +83 ° ~ +90°
LOSS ON DRYING 0.5% max OTHER INFORMATION
Hazard Symbols: T, Risk Phrases: 45-22-63, Safety Phrases: 53-36/37-45
UNUSUAL FIRE AND EXPLOSION HAZARDS
This material is assumed to be combustible. When heated to decomposition (as under fire conditions) it may emit toxic fumes. REACTIVITY HAZARD DATA
STABILITY: Stable ( X ) Unstable ( )
INCOMPATIBILITY (MATERIALS TO AVOID): Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS: When heated to decomposition it may emit toxic fumes.
HAZARDOUS POLYMERIZATION: May Occur ( ) Will Not Occur ( X )
TOXICOLOGICAL INFORMATION
Target organs: Reproductive system
ORL-RAT LD50: 1000 mg/kg
IHL-RAT LC50: N.A.
SKN-RBT LD50: N.A.
Testosterone propionate is similar to enanthate, cypionate, and sustanon. However, compared to enanthate or cypionate, propionate is a much shorter ester and will release more quickly into the bloodstream. As a result of its short action, more frequent (daily) injections are required to prevent steroid blood levels from tapering down and becoming ineffective. An injection schedule of every third day is about the longest you would want to perform using propionate to achieve good results. For best results - daily injections are more suitable given the nature of this agent. Peak propionate levels take place after 24-36 hours and taper down from there. As a result of the frequency of injections required of propionate, it is not a very attractive steroid for those who are doing their first cycle or those who do not like intra-muscular injections to begin with. For a first cycle, a longer acting, single ester testosterone such as enanthate or cypionate or preferred because in both cases few injections can be made while maintaining stable blood levels and thereby optimizing results. Respectively, enanthate should be injected twice weekly and cypionate once weekly. Since both yield similar results, the first time user would more likely enjoy either of those two compounds over propionate. The benefits of propionate may not be worth the additional energy required for the injections. Propionate is also a relatively painful steroid to inject with uses complaining that the same spots become aggravated with additional injections which require injecting in several different places for prevention of this pain. The injection site may become irritated and users have complained of long lasting pain caused by the injections. For these reasons, propionate is not such a good idea for the first time steroid user, however, enanthate and cypionate are not without their share of complications and all factors should be assessed before beginning with any steroid cycle. If propionate is the steroid of choice, ancillary drugs such as nolvadex, proviron and arimidex are advised to have on hand during the cycle in case symptoms of gyno arise (or if you wish, you can run these drugs during the cycle for prevention). All testosterones will aromatize, although some have a lesser chance of it. Propionate may be one of those drugs, but proper precautions should be taken, nevertheless.
Testosterone propionate has a short active life of 2-3 days. It has a short half life and is active in the system only a day after injection. Propionate is one of the componenets of the four testosterone ester blend sustanon, and, along with phenylpropionate, is the reason why more frequent injections are required with sustanon (to take full advantage of all esters in the blend). Propionate has the same benefits of every other testosterone along with the advantage of being fast acting. Another advantage of propionate when compared to other steroids is that the level of water retention and water based gains on cycle are lower when compared to counterparts such as testosterone enanthate or testosterone cypionate. The benefits of testosterone, such as improved muscle pumps can be seen very soon after propionate is administered due to its short half life and related length of activation.
Propionate does have a high rate of aromatization, similar to any other testosterone, and as a result, ancillary drugs such as nolvadex or its weaker counterpart clomid should be kept on hand during a cycle where propionate is included to stop gyno from occurring.
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